Pax-2 antigene expression in kidney tumours
نویسندگان
چکیده
منابع مشابه
Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor.
Although both the renin angiotensin system (RAS) and the paired homeobox 2 gene (Pax-2) seem critically important in renal organogenesis, whether and how they might interact has not been addressed. The present study asked whether a link between the RAS and Pax-2 exists in fetal renal cells, speculating that such an interaction, if present, might influence renal development. Embryonic kidney exp...
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Introduction A variety of benign and malignant tumours can arise in the kidney in children. With minor variations, the spectrum of tumours has worldwide distribution. Wilms’ tumour (WT; also known as nephroblastoma) is the most common kidney tumour in childhood, and may represent the most common abdominal tumour presenting in infants and children in sub-Saharan Africa. In the past decade, consi...
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During embryonic development, the anterior-posterior body axis is specified in part by the combinatorial activities of Hox genes. Given the poor DNA binding specificity of Hox proteins, their interaction with cofactors to regulate target genes is critical. However, few regulatory partners or downstream target genes have been identified. Herein, we demonstrate that Hox11 paralogous proteins form...
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ژورنال
عنوان ژورنال: Acta chirurgica Iugoslavica
سال: 2011
ISSN: 0354-950X,2406-0887
DOI: 10.2298/aci1104015v